SCIENTIFIC PROGRAM
19th International Workshop on Osteoarthritis Imaging
ANATOMY: the basis of shape, structure & function
General Information
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All scientific sessions and lunches will take place at Cripps Court Conference Centre, Magdalene College, Cambridge, 1-3 Chesterton Rd, Cambridge CB4 3AD. Conference attendees will have access to all college grounds during the conference. Accommodation details will be released in due course, but there will be rooms available on site.
All speakers are confirmed but may be subject to change. Talk titles are representative for the session topic and will be confirmed closer to the event
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Conference Organisers
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Prof. Tom Turmezei, Norfolk and Norwich University Hospital, Norwich, UK
Prof. Cecilia Brassett, University of Cambridge, UK
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ISOAI President
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Prof. Ali Guermazi, Boston University Medical Center, USA
Program
DAY 1 - WEDNESDAY 9TH JULY 2025
All Times are in BST (GMT+1)
10:00-12:00 PRE-CONFERENCE WORKSHOP
Human Anatomy Centre, Anatomy Building, Downing Site, Cambridge, CB2 3DY
*This is a costed ticketed event with limited numbers
11:30 REGISTRATION OPENS
At conference venue
12:30-13:30 LUNCH
At conference venue
13:30-14:00 CONFERENCE OPENING
Welcome from ISOAI President, Prof. Ali Guermazi
Welcome from IWOAI 2025 hosts, Prof. Tom Turmezei & Prof. Cecilia Brassett
14:00-15:30 SESSION 1 - QUANTITATIVE MRI - Latest in structure & function
Chair: Shadpour Demehri, Johns Hopkins University of Medicine, USA​
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14:00-14:20 K1.1 Keynote speaker 1 - Rupsa Bhattacharjee - Quantitative MRI
14:20-14:40 K1.2 Keynote speaker 2 - Feliks Kogan - PET-MRI
14:40-14:50 Questions and discussion
14:50-15:03 S1.1 Ananya Goyal, USA
THE AGING JOINT: QUANTITATIVE [18F]NAF PET-MR IMAGING OF CELLULAR & MOLECULAR CHANGES IN BONE, CARTILAGE AND MUSCLE ACROSS THE LIFESPAN
15:03-15:16 S1.2 Vidyani Suryadevara, USA
CLINICAL TRANSLATION PIPELINE FOR DETECTING SENESCENCE IN OSTEOARTHRITIS USING THE BGALACTOSIDASE RESPONSIVE GD-CHELATE
15:16-15:30 S1.3 Krithika Balaji, UK
COMPARATIVE STUDY: QDESS VERSUS RAFO-4 PERFORMANCE IN 5-MINUTE, SIMULTANEOUS, RELIABLE 3D T2 MAPPING AND MORPHOLOGICAL MR IMAGING
15:30-16:30 BREAK WITH REFRESHMENTS inc. GUIDED POSTER TOURS
16:30-18:00 SESSION 2 - MICRO-CT IN OSTEOARTHRITIS - Scaling up with CT
Chair: Sarah Mankse University of Calgary, Canada
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16:30-16:50 K2.1 Keynote speaker 1 - Kathryn Stok - The spectrum of micro-CT in osteoarthritis
16:50-17:10 K2.2 Keynote speaker 2 - Andrew Pitsillides - Imaging animal models of osteoarthritis
17:10-17:20 Questions and discussion
17:20-17:33 S2.1 Andy Kin On Wong, Canada
COMPROMISED TRABECULAR BONE OF THE KNEE IS A DOSE-DEPENDENT CORRELATE OF MORE SEVERE OSTEOPHYTES AND ADVANCED KLG
17:33-17:46 S2.2 Neil Segal, USA
EVALUATION OF DIFFERENT METHODS OF AUTOMATED 3-D JOINT SPACE MAPPING FROM WEIGHT BEARING CT SUGGESTS A TIBIAL MESH-TO-MESH APPROACH IS MOST SENSITIVE
17:46-18:00 S2.3 Ali Guermazi, USA
PHASE II RANDOMISED CLINICAL TRIAL OF LEVI-04, A NOVEL NEUROTROPHIN-3 INHIBITOR, IN PEOPLE WITH KNEE OSTEOARTHRITIS: IMAGING EXCLUSIONS DURING SCREENING
18:00-18:15 Osteoarthritis Imaging Prof. Frank Roemer - Editor-in-Chief
19:30-23:30 DINNER EVENT
The Maharajah Restaurant, 9-13 Castle St., Cambridge, CB3 0AH
*This is a costed ticketed event with limited numbers​
DAY 2 - THURSDAY 10TH JULY 2025
09:00-11:00 SESSION 3 - COHORTS vs CLINICAL TRIALS - Strength in numbers?
Chair: David Hunter University of Sydney, Australia
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09:00-09:20 K3.1 Keynote speaker 1 - Neil Segal - The past, present and future WBCT in MOST
09:20-09:40 K3.2 Keynote speaker 2 - Jamie MacKay - Experimental trial options in osteoarthritis
09:40-09:50 Questions and discussion
09:50-11:00 P1 Clinical Trials Panel - "The Last 12 Months"
David Hunter - University of Sydney, Australia (chair)
Klaus Flechsenhar - Sanofi
Olga Kubassova - IAG
Simon Westbrook - Levicept
Kent Kwoh - University of Arizona, USA
11:00-11:30 BREAK WITH REFRESHMENTS
11:30-12:30 SESSION 4 - JOINT BIOLOGY & IMAGING - From tissue to pixel
Chair: Frank Roemer University of Erlangen-Nuremberg, Germany
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11:30-11:50 K4.1 Keynote speaker 1 - Tonia Vincent - Molecular endotypes and clinical phenotypes in STEpUP OA
11:50-12:10 K4.2 Keynote speaker 2 - Andrew McCaskie - Translation, stratification and regeneration in OA
12:10-12:20 Questions and discussion
12:20-12:33 S4.1 Simon Westbrook, UK LEVI-04 REDUCES BONE MARROW LESION AREA AND PRESENCE IN KNEE OSTEOARTHRITIS: RESULTS FROM A PHASE II RCT
12:30-14:00 LUNCH
Optional Samuel Pepys Tour
*This is a free ticketed event with limited numbers
14:00-15:30 SESSION 5 - SHAPE IN OSTEOARTHRITIS - “Built to fail?”
Chair: Alan Brett Stryker
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14:00-14:20 K5.1 Keynote speaker 1 - Jenny Gregory - Shape, osteoarthritis risks and outcomes
14:20-14:40 K5.2 Keynote speaker 2 - Anthony Gatti - MRI, shape and other parameters
14:40-14:50 Questions and discussion
14:50-15:03 S5.1 Fleur Boel, The Netherlands
BEYOND ACETABULAR DYSPLASIA AND PINCER MORPHOLOGY: REFINING HIP OSTEOARTHRITIS RISK ASSESSMENT THROUGH STATISTICAL SHAPE MODELING
15:03-15:16 S5.2 Anoosha Pai, USA
NEURAL SHAPE MODEL QUANTIFIES EARLY AND PROGRESSIVE BONE SHAPE CHANGES AFTER ACLR
15:16-15:30 S5.3 Myrthe van den Berg, The Netherlands
ADVANCING HIP OSTEOARTHRITIS PREDICTION: INSIGHTS FROM MULTI-MODAL PREDICTIVE MODELING WITH INDIVIDUAL PARTICIPANT DATA OF THE WORLD COACH CONSORTIUM
15:30-16:30 BREAK WITH REFRESHMENTS inc. GUIDED POSTER TOURS
16:30-18:00 SESSION 6 - LATEST IN COMPUTED TOMOGRAPHY - A CT world
Chair: Mikael Boesen University of Copenhagen, Denmark​
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16:30-16:50 K6.1 Keynote speaker 1 - Edwin Oei - Photon counting CT for osteoarthritis
16:50-17:10 K6.2 Keynote speaker 2 - Graham Treece - CT, bone, and data visualisation
17:10-17:20 Questions and discussion
17:20-17:33 S6.1 Mohamed Jarraya, USA
PHOTON-COUNTING CT-BASED TRABECULAR BONE ANALYSIS IN THE KNEE: A COMPARATIVE STUDY OF ADVANCED OSTEOARTHRITIS AND HEALTHY CONTROLS
17:33-17:46 S6.2 Susan Li, USA
BASELINE C-SCORE ON WEIGHT-BEARING CT PREDICTS 2-YEAR WORSENING OF KNEE PAIN IN WOMEN
17:46-18:00 S6.3 Tom Turmezei, UK
REPEATABILITY OF CT OSTEOARTHRITIS KNEE SCORE (COAKS) AND A PROTOTYPE CT-GENERATED KELLGREN AND LAWRENCE GRADE
18:00-18:15 Day close
19:30-23:30 DINNER EVENT
The Graduate by Hilton Hotel Cambridge
Including pre-dinner drinks and entertainment
*This is a costed ticketed event with limited numbers​
DAY 3 - FRIDAY 11TH JULY 2025
09:00-10:30 SESSION 7 - LATEST AI IN OSTEOARTHRITIS IMAGING - “Hype of the machines”
Chair: Olga Kubassova IAG
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09:00-09:20 K7.1 Keynote speaker 1 - Akshay Chaudhuri - AI segmentation techniques
09:20-09:40 K7.2 Keynote speaker 2 - Aleksei Tiulpin - Multimodal AI in adaptive clinical trials
09:40-09:50 Questions and discussion
09:50-10:03 S7.1 Anthony Gatti, USA
AUTOMATIC MENISCUS ANALYSIS DEMONSTRATES REPAIR IS NOT SUPERIOR TO MENISCECTOMY IN IMPROVING MENISCAL UTE-T2* PROPERTIES 2-YEARS POST ACLR
10:03-10:16 S7.2 Rayan Harari, USA
PREDICTING KNEE OSTEOARTHRITIS PROGRESSION USING EXPLAINABLE MACHINE LEARNING AND CLINICAL IMAGING DATA
10:16-10:30 S7.3 Wolfgang Wirth, Austria
A FULLY-AUTOMATED TECHNIQUE FOR KNEE CARTILAGE AND DENUDED BONE AREA MORPHOMETRY IN SEVERE RADIOGRAPHIC KNEE OA – METHOD DEVELOPMENT AND VALIDATION
10:30-11:00 BREAK WITH REFRESHMENTS
11:00-12:30 SESSION 8 - ANATOMY & OSTEOARTHRITIS - “A blueprint for motion”
Chair: Cecillia Brassett University of Cambridge, UK
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11:00-11:20 K8.1 Keynote Speaker 1 - Felix Eckstein - Sex differences in osteoarthritis anatomy
11:20-11:40 K8.2 Keynote Speaker 2 - Piers Mitchell - Archaeology, anthropology and OA
11:40-11:50 Questions and discussion
11:50-12:03 S8.1 Noël Spoedler, The Netherlands
TOPOGRAPHY OF SEX-RELATED FEMOROTIBIAL CARTILAGE THICKNESS DIFFERENCES: A MATCHED MALE-FEMALE PAIR ANALYSIS CONTROLLING FOR AGE, BMI, AND HEIGHT
12:03-12:16 S8.2 Jamie Collins, USA
DATA-DRIVEN DISCOVERY OF KNEE OSTEOARTHRITIS SUBGROUPS VIA CLUSTER ANALYSIS OF MRI BIOMARKERS
12:16-12:30 S8.3 Philip Conaghan, UK
LEVI-04, A NOVEL NEUROTROPHIN-3 INHIBITOR, DEMONSTRATED SIGNIFICANT IMPROVEMENTS IN PAIN AND FUNCTION AND WAS NOT ASSOCIATED WITH DELETERIOUS EFFECTS ON JOINT STRUCTURE IN PEOPLE WITH KNEE OA IN A PHASE II RCT
12:30-14:00 LUNCH
Optional Samuel Pepys Tour
*This is a free ticketed event with limited numbers
14:00-15:30 SESSION 9 - BIOMECHANICS & IMAGING - “A moving target”
Chair: Constance Chu Standford University, California, USA
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14:00-14:20 K9.1 Keynote speaker 1 - Erin Macri - Gait, imaging and OA
14:20-14:40 K9.2 Keynote speaker 2 - Jari Salo - Weight bearing CT in orthopaedic practice
14:40-14:50 Questions and discussion
14:50-15:03 S9.1 Jordan Broberg, Canada
EFFECT OF LATERAL MENISCUS POSTERIOR ROOT TEARS ON CARTILAGE AND MENISCAL MECHANICS
15:03-15:16 S9.2 Rosemarijn van Paassen, The Netherlands
PATELLAR AND FEMORAL BONE MORPHOLOGY AND ITS ASSOCIATION WITH LOADING IN YOUNG ADOLESCENT BOYS AND GIRLS
15:16-15:30 S9.3 Zhe Wang, USA
DEEP LEARNING MODELS FOR AUTOMATIC JOINT SPACE WIDTH MEASUREMENT
15:30-16:30 BREAK WITH REFRESHMENTS inc. GUIDED POSTER TOURS
16:30-17:30 SESSION 10 - Gulf of America - the immediate future of international research challenges in the USA
Chair: Tom Turmezei Norfolk and Norwich University Hospital, Norwich, UK​
17:30-17:45 AWARD CEREMONY
Young Investigator Awards
Top abstract Awards
Top poster Awards
17:45-18:00 WELCOME TO IWOAI 2026, MUNICH, GERMANY
Prof. Frank Roemer & Dr. Wolfgang Wirth
18:00 CONFERENCE CLOSE
19:30-22:00 GALA DINNER
The Hall, Magdalene College, Cambridge
Including pre-dinner drinks reception and entertainment
*This is a costed ticketed event with limited numbers
SOCIAL DAY - SATURDAY 12TH JULY 2025
10:00 - 12:00 WALKING TOUR OF CAMBRIDGE
See a different side of Cambridge with Terrible Tours of Cambridge
*This is a part of the day’s costed ticketed package with limited numbers
12:00 - 14:00 LUNCH
The Hall, Christ’s College, Cambridge
Ticket holders will have access to all college grounds around the event
*This is a part of the day’s costed ticketed package with limited numbers
14:00 - 14:30 Walking from Christ’s College to the Mill Pond for punting
14:30 - 16:30 PUNTING ON THE CAM
Punt yourself along the beautiful Backs of Cambridge from Scudamore’s
*This is a part of the day’s costed ticketed package with limited numbers
18:00 until late CAMBRIDGE BY NIGHT
Relive student days on a tour of the finest establishments Cambridge has to offer
*This is a non-ticketed post-conference tour open to one-and-all