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18th International Workshop on Osteoarthritis Imaging 
Structure and Pain: Where are we today?

Chairs

Ali Guermazi, MD, PhD, Boston University School of Medicine, Boston, MA/USA

Scientific Committee

Jamie Collins

Sarah Ghobrial

Ananya Goyal

Jessica Kupper

Vidyani Suryadevara

Local Organizers

Ali Guermazi, MD, PhD, Boston University School of Medicine, Boston, MA/USA

Najat Cherif Idrissi, MD, University Hospital Arrazi, Marrakech, Morocco

Mariem Ouali Idrissi, MD, University Hospital Arrazi, Marrakech, Morocco

Program

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Day 1
Tuesday, June 25, 2024

All times are CET

10:00 - 12:00 Guided tour in the old city of Marrakech

14:15 - 14:30 Opening: Ali Guermazi (Chair of the meeting)

14:30 - 16:00 Session 1: “Pain in OA: Clinical trials”

         

    14:30 - 14:45 Keynote speakerPain in OA: nociceptive, neuropathic, and nociplastic – all relevant in                                                                  clinical trials? - Kent Kwoh

    14:45 - 15:00 Keynote speakerUpdate structure modification and translation to clinical benefit                                                                            - Frank Roemer 
    15:00 - 16:00 Four abstracts

16:00 - 16:30 Break 

16:30 - 18:00 Session 2: “Pain in OA: Novel concepts”

    16:30 - 16:45 Keynote speaker: Understand central sensitization and relevance for OA clinical trials                                                                    - David Walsh

    16:45 - 17:00 Keynote speaker: Radiology is more than looking at MRIs: Practical aspects of                                                                               interventional treatment of pain in OA – Yan Epelboym

    17:00 - 17:15 Keynote speaker: Genicular artery embolization for pain treatment in patients with knee

                                                         OA: Results from clinical trials – Edwin Oei    

    17:15 - 18:00 Four abstracts

18:00 - 18:10 Acknowledgements of Young Investigator Award winners

           

    Three best abstracts


18:10 - 18:30 IWOAI/ISOAI businesses

 

    Ali Guermazi, President

    Frank Roemer, Editor-in-Chief, Osteoarthritis Imaging

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Day 2
Wednesday, June 26, 2024

09:00 - 10:30 Session 3: “Bone”

    09:00 - 09:15 Keynote speaker: Bone (BMLs and osteophytes) and pain: current understanding                                                                                – Ali Mobasheri 

    09.15 - 09.30 Keynote speaker: Imaging of BML in research and clinical practice (MRI, DECT, PET-CT, AI)

                                                         – Shadpour Demehri

    09:30 - 09:45 Keynote speaker: Imaging of BMLs in clinical trials – John Carrino

    09:45 - 10:20 Three abstracts

10:30 - 11.00 Break

11:00 - 12:30 Session 4: “Synovitis and Inflammation?”

     11:00 - 11:15 Keynote speaker: Synovitis and pain – Francis Berenbaum

     11:15 - 11:30 Keynote speaker: Established assessment of inflammation in clinical trials – Daichi Hayashi

     11:30 - 11:45 Keynote speaker: Advanced imaging of inflammation in clinical trials and novel approaches                                                               (including Nuclear Medicine) – Mikael Boesen
     11:45 - 12.30 Four abstracts

12:30 - 12.45 Poster pitches

12:45 - 13.45 Lunch

13:45 - 14.30 Poster session

14:30 - 16:00 Session 5: “Cartilage and Meniscus”

    14:30 - 14:45 Keynote speaker: Is cartilage and meniscus painful or not? – Jeff Katz

    14:45 - 15:00 Keynote speaker: Imaging of cartilage and meniscus: role of MRI and CT – Patrick Omoumi

    15:00 - 16:00 Four abstracts

16:00 - 16:30 Break

16:30 - 18:00 Session 6: “Pain: Challenges and chances”

    16:30 - 16:45 Keynote speaker: Placebo and regression to the mean – how to deal with them when it comes                                                           to pain assessment in clinical trials – Elena Losina

    16:45 - 17:00 Keynote speaker: AI and pain in OA clinical trials: Where it may make a difference or aren’t                                                               we there yet? – Simo Saarakkala

    17:00 - 18:00 Four abstracts

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Day 3
Thursday, June 27, 2024

09:00-10:30 Session 7: “Structural Phenotyping in clinical trials”

    09:00 - 09:15 Keynote speaker: Analytic challenges in defining structural phenotypes in OA clinical trials

                                                         – Jamie Collins

    09:15 - 09:30 Keynote speaker: Enrichment by imaging – Philip Conaghan

    09:30 - 09:45 Keynote speaker: Introducing the theratype – David Hunter

    09:45 - 10:30 Four abstracts

10:30 - 11:00 Break

11:00 - 12:30 Session 8: “An update on ongoing clinical trials – Future perspectives”

    11:00 - 11:15 Keynote speaker: Before KL2 and 3: Potentials and challenges of imaging in trials – Martin Englund

    11:15 - 11:30 Keynote speaker: Overview of current ongoing clinical trials in OA – Marc Hochberg

    11:30 - 11:45 Keynote speaker: Role of imaging in Pain clinical trials – Ali Guermazi

    11:45 - 12:30 Three abstracts

12:30 - 12:45 Poster pitches

12:45 - 13:45 Lunch

13:45 - 14:30 Poster session

 

14:30 - 16:00 Session 9: “Imaging outcomes in clinical trials – what should we use?”

    14.30 - 14.45 Keynote speaker: A pre-defined structure tailored to the mode of action – Felix Eckstein

    14.45 - 15.00 Keynote speaker: A composite outcome – David Felson

    15.00 - 16.00 Four Abstracts


16:00 - 16:30 Break

16:30 - 18:00 Session 10: “Clinical trials – where do we go from here” (Round Table)

    16:30 - 17:30 Tim McAlindon, David Hunter, Stefan Lohmander, Moon Jong Noh, Klaus Flechsenhar

    17:30 - 18:00 Panel discussion

18:00 - 18:30 Adjourn and invitation to IWOAI 2025: Tom Turmezei and Jamie MacKay (Cambridge, UK)

 

19:30 - 23:00 Gala dinner

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Day 4
Friday, June 28, 2024

9:00 – 19:00               

 

Day visit to Essaouira (former Mogador), a port city with amazing scenery on the Atlantic Ocean

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