18th International Workshop on Osteoarthritis Imaging
Structure and Pain: Where are we today?
Chairs
Ali Guermazi, MD, PhD, Boston University School of Medicine, Boston, MA/USA
Scientific Committee
Jamie Collins
Sarah Ghobrial
Ananya Goyal
Jessica Kupper
Vidyani Suryadevara
Local Organizers
Ali Guermazi, MD, PhD, Boston University School of Medicine, Boston, MA/USA
Najat Cherif Idrissi, MD, University Hospital Arrazi, Marrakech, Morocco
Mariem Ouali Idrissi, MD, University Hospital Arrazi, Marrakech, Morocco
Program
Day 1
Tuesday, June 25, 2024
All times are CET
10:00 - 12:00 Guided tour in the old city of Marrakech
14:15 - 14:30 Opening: Ali Guermazi (Chair of the meeting)
14:30 - 16:00 Session 1: “Pain in OA: Clinical trials”
14:30 - 14:45 Keynote speaker: Pain in OA: nociceptive, neuropathic, and nociplastic – all relevant in clinical trials? - Kent Kwoh
14:45 - 15:00 Keynote speaker: Update structure modification and translation to clinical benefit - Frank Roemer
15:00 - 16:00 Four abstracts
16:00 - 16:30 Break
16:30 - 18:00 Session 2: “Pain in OA: Novel concepts”
16:30 - 16:45 Keynote speaker: Understand central sensitization and relevance for OA clinical trials - David Walsh
16:45 - 17:00 Keynote speaker: Radiology is more than looking at MRIs: Practical aspects of interventional treatment of pain in OA – Yan Epelboym
17:00 - 17:15 Keynote speaker: Genicular artery embolization for pain treatment in patients with knee
OA: Results from clinical trials – Edwin Oei
17:15 - 18:00 Four abstracts
18:00 - 18:10 Acknowledgements of Young Investigator Award winners
Three best abstracts
18:10 - 18:30 IWOAI/ISOAI businesses
Ali Guermazi, President
Frank Roemer, Editor-in-Chief, Osteoarthritis Imaging
Day 2
Wednesday, June 26, 2024
09:00 - 10:30 Session 3: “Bone”
09:00 - 09:15 Keynote speaker: Bone (BMLs and osteophytes) and pain: current understanding – Ali Mobasheri
09.15 - 09.30 Keynote speaker: Imaging of BML in research and clinical practice (MRI, DECT, PET-CT, AI)
– Shadpour Demehri
09:30 - 09:45 Keynote speaker: Imaging of BMLs in clinical trials – John Carrino
09:45 - 10:20 Three abstracts
10:30 - 11.00 Break
11:00 - 12:30 Session 4: “Synovitis and Inflammation?”
11:00 - 11:15 Keynote speaker: Synovitis and pain – Francis Berenbaum
11:15 - 11:30 Keynote speaker: Established assessment of inflammation in clinical trials – Daichi Hayashi
11:30 - 11:45 Keynote speaker: Advanced imaging of inflammation in clinical trials and novel approaches (including Nuclear Medicine) – Mikael Boesen
11:45 - 12.30 Four abstracts
12:30 - 12.45 Poster pitches
12:45 - 13.45 Lunch
13:45 - 14.30 Poster session
14:30 - 16:00 Session 5: “Cartilage and Meniscus”
14:30 - 14:45 Keynote speaker: Is cartilage and meniscus painful or not? – Jeff Katz
14:45 - 15:00 Keynote speaker: Imaging of cartilage and meniscus: role of MRI and CT – Patrick Omoumi
15:00 - 16:00 Four abstracts
16:00 - 16:30 Break
16:30 - 18:00 Session 6: “Pain: Challenges and chances”
16:30 - 16:45 Keynote speaker: Placebo and regression to the mean – how to deal with them when it comes to pain assessment in clinical trials – Elena Losina
16:45 - 17:00 Keynote speaker: AI and pain in OA clinical trials: Where it may make a difference or aren’t we there yet? – Simo Saarakkala
17:00 - 18:00 Four abstracts
Day 3
Thursday, June 27, 2024
09:00-10:30 Session 7: “Structural Phenotyping in clinical trials”
09:00 - 09:15 Keynote speaker: Analytic challenges in defining structural phenotypes in OA clinical trials
– Jamie Collins
09:15 - 09:30 Keynote speaker: Enrichment by imaging – Philip Conaghan
09:30 - 09:45 Keynote speaker: Introducing the theratype – David Hunter
09:45 - 10:30 Four abstracts
10:30 - 11:00 Break
11:00 - 12:30 Session 8: “An update on ongoing clinical trials – Future perspectives”
11:00 - 11:15 Keynote speaker: Before KL2 and 3: Potentials and challenges of imaging in trials – Martin Englund
11:15 - 11:30 Keynote speaker: Overview of current ongoing clinical trials in OA – Marc Hochberg
11:30 - 11:45 Keynote speaker: Role of imaging in Pain clinical trials – Ali Guermazi
11:45 - 12:30 Three abstracts
12:30 - 12:45 Poster pitches
12:45 - 13:45 Lunch
13:45 - 14:30 Poster session
14:30 - 16:00 Session 9: “Imaging outcomes in clinical trials – what should we use?”
14.30 - 14.45 Keynote speaker: A pre-defined structure tailored to the mode of action – Felix Eckstein
14.45 - 15.00 Keynote speaker: A composite outcome – David Felson
15.00 - 16.00 Four Abstracts
16:00 - 16:30 Break
16:30 - 18:00 Session 10: “Clinical trials – where do we go from here” (Round Table)
16:30 - 17:30 Tim McAlindon, David Hunter, Stefan Lohmander, Moon Jong Noh, Klaus Flechsenhar,
Francis Berenbaum
17:30 - 18:00 Panel discussion
18:00 - 18:30 Adjourn and invitation to IWOAI 2025: Tom Turmezei and Cecilia Brassett (Cambridge, UK)
19:30 - 23:00 Gala dinner
Day 4
Friday, June 28, 2024
9:00 – 19:00
Day visit to Essaouira (former Mogador), a port city with amazing scenery on the Atlantic Ocean